Reassessing After-Hour Arrival Patterns and Outcomes in ST-Elevation Myocardial Infarction
James Langabeer1, Diaa Alqusairi2, Jami L DelliFraine3
1University of Texas Health Science Center, Houston, Texas.
Patients arriving at ST-elevation myocardial infarction (STEMI) centers on weekends or after hours experience longer door-to-balloon times and increased in-hospital mortality, indicating persistent disparities in STEMI treatment.
Area of Science:
- Cardiology
- Health Services Research
Background:
- ST-elevation myocardial infarction (STEMI) center performance may vary outside of regular hours.
- After-hours capability can potentially impact patient outcomes for STEMI cases.
Purpose of the Study:
- To investigate the impact of weekend vs. weekday and business vs. after-hours presentation on door-to-balloon (D2B) times and in-hospital mortality for STEMI patients.
- To identify disparities in STEMI treatment during non-standard hours.
Main Methods:
- Prospective observational study of 1,247 non-transfer STEMI patients.
- Analysis of data from 15 percutaneous coronary intervention (PCI) facilities in Dallas, Texas (2010-2012).
- Statistical control for confounding factors to compare D2B times and mortality based on presentation timing (weekends/after-hours vs. weekdays/business hours).
Main Results:
- Patients presenting on weekends had significantly longer D2B times (75 vs. 65 minutes) compared to weekdays.
- After-hours arrivals experienced median D2B times over 16 minutes longer than business-hour arrivals.
- After-hours presentation was associated with a 2.23-fold increased likelihood of in-hospital mortality.
Conclusions:
- Weekend and after-hours percutaneous coronary intervention (PCI) coverage is linked to adverse D2B outcomes and higher in-hospital mortality.
- Significant disparities persist in the treatment of STEMI patients presenting outside of standard business hours, even in urban centers.
- The findings underscore the need for improved resource allocation and protocols to ensure equitable STEMI care across all hours.
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