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Wave detection in acceleration plethysmogram.
1Department of Electronics Engineering, College of Information and Electronics Engineering, Hallym University, Chuncheon, Korea.
Healthcare Informatics Research
|May 22, 2015
Summary
A new algorithm and preamplifier can accurately detect acceleration plethysmogram (APG) wave indices from photoplethysmography (PPG) signals. This technology aids in simple, real-time vascular aging evaluation for early atherosclerosis screening.
Area of Science:
- Biomedical Engineering
- Cardiovascular Physiology
- Signal Processing
Background:
- Photoplethysmography (PPG) and its second derivative, acceleration plethysmography (APG), show promise for predicting atherosclerosis risk factors.
- Extracting APG wave indices (a, b, c, d) from fingertip PPG signals presents significant challenges for early disease detection.
Purpose of the Study:
- To develop a novel wave detection algorithm and preamplifier for accurate APG signal analysis.
- To enable real-time extraction of APG wave indices for improved cardiovascular health assessment.
Main Methods:
- Utilized the 4th order derivative of PPG to enhance APG waveform separation and wave detection success rates.
- Designed a preamplifier with a Sallen-Key low pass filter and a microcontroller-based wave detection algorithm.
- Incorporated programmable gain control, mathematical differentials, and a digital IIR notch filter for signal processing.
Main Results:
- The digital IIR filter's frequency response was evaluated, and a pulse train for wave index identification was generated.
- Programmable gain control ensured consistent APG amplitude output despite variations in PPG input.
- The mean value of the a wave index was 1,106.45 ± 47.75 in 164 subjects.
Conclusions:
- The proposed algorithm and preamplifier effectively extract APG wave indices in real-time.
- This technology offers a simple and valuable tool for assessing vascular aging.
- The findings support the use of this system in basic healthcare devices for cardiovascular evaluation.
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