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Related Concept Videos

Hypodermis01:02

Hypodermis

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The hypodermis (the subcutaneous layer or superficial fascia) is present directly below the dermis. It connects the skin to the underlying fascia (fibrous tissue) of the bones and muscles. It is not strictly a part of the skin, although the border between the hypodermis and dermis can be difficult to distinguish. The hypodermis consists of well-vascularized, loose, areolar connective tissue and adipose tissue, which functions as a mode of fat storage and provides insulation and cushioning for...
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Related Experiment Video

Updated: Apr 12, 2026

Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
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Brown Adipose Tissue: A Human Perspective.

Mariëtte R Boon1, Wouter D van Marken Lichtenbelt2

  • 1Maastricht University, Maastricht, The Netherlands.

Handbook of Experimental Pharmacology
|May 25, 2015
PubMed
Summary
This summary is machine-generated.

Brown adipose tissue (BAT) in adults, discovered in 2009, significantly impacts metabolism. Activating this brown fat may offer a novel strategy for managing obesity and related metabolic disorders.

Keywords:
Beige adipocytesBrown adipocytesCold acclimationEnergy expenditurePET-CT scansPharmacology

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Area of Science:

  • Metabolic Research
  • Human Physiology
  • Obesity Studies

Background:

  • Brown adipose tissue (BAT) presence in adult humans confirmed since 2009.
  • Active BAT contributes significantly to human resting metabolic rate (2.5-5%).
  • BAT activation holds potential for alleviating obesity and associated metabolic disorders.

Purpose of the Study:

  • Discuss the discovery of BAT in adult humans.
  • Detail the characteristics of human BAT.
  • Outline methods for visualizing and enhancing BAT activity.

Main Methods:

  • Literature review on BAT discovery and characteristics.
  • Exploration of imaging techniques for BAT visualization.
  • Overview of physiological and pharmacological interventions for BAT activation.

Main Results:

  • Established presence and metabolic significance of adult human BAT.
  • Identified key characteristics of human BAT.
  • Cataloged various methods to assess and stimulate BAT.

Conclusions:

  • Adult human BAT is a validated metabolic tissue.
  • Understanding BAT is crucial for developing anti-obesity strategies.
  • Further research into BAT activation methods is warranted.