[Gastro-esophageal reflux and asthma. Clinical experience]
Related Experiment Video
Updated: Oct 22, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
Abstract:
Gastroesophageal reflux (GER) may contribute to the persistence of asthma and may be triggered and/or exacerbated by treatment with bronchodilatory and cortisone drugs. For this reason, GER should be suspected in patients with asthma non-responsive to treatment. In fact in this series 24 hour pH monitoring revealed GER in 7 out of 9 (77%) patients with persistent asthma. The use of a personally developed diagnostic protocol permitted the identification of various situations in 4 patients who completed the study: one coincidental association, one GER caused by theophylline and constituting the main cause of the bronchial obstruction.
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