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Updated: Apr 11, 2026

Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
[Anaesthesia for patients with chronic wounds]
Mathias Hjort1, Mette Hyllested, Bo Jørgensen
1Frederiksborggade 27, 2. th., 1360 København K. mathiashjort@hotmail.com.
Ultrasound-guided peripheral nerve blocks (PNB) offer a minimally invasive anesthesia option for chronic wound surgery. This approach supports continued anticoagulation, reduces opioid use, and improves patient mobility post-surgery.
Area of Science:
- Surgical Anesthesiology
- Wound Management
Background:
- Chronic wounds require multidisciplinary perioperative management.
- Severe comorbidities increase post-operative complication risks in these patients.
- Minimally invasive techniques optimize wound healing.
Purpose of the Study:
- To evaluate ultrasound-guided peripheral nerve blocks (PNB) as an anesthesia method for chronic wound surgeries.
- To highlight the benefits of PNB in patients with comorbidities undergoing wound procedures.
Main Methods:
- Application of ultrasound-guided peripheral nerve blocks (PNB) for surgical procedures.
- Anesthesiological and surgical management of patients with chronic wounds and comorbidities.
Main Results:
- PNB is an ideal anesthesia for wound revisions, amputations, and skin grafting.
- PNB facilitates continued anticoagulant therapy.
- PNB provides effective post-operative analgesia and reduces opioid consumption.
- PNB aids in early patient mobilization.
Conclusions:
- Ultrasound-guided PNB is a safe and effective anesthetic technique for perioperative wound management.
- PNB improves outcomes in high-risk patients by enabling minimally invasive procedures and enhancing recovery.
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