Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Steady, Laminar Flow in Circular Tubes

Steady, Laminar Flow in Circular Tubes

Hagen-Poiseuille flow describes a viscous fluid's steady, incompressible flow through a cylindrical tube with a constant radius R. This flow profile is often applied to understand fluid transport in narrow channels, such as capillaries. It serves as a foundational example of laminar flow. In this model, cylindrical coordinates (r,θ,z) are used to describe the radial (r), angular (θ), and axial (z) dimensions within the tube. For Hagen-Poiseuille flow, the velocity profile is purely axial,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Quaternary aminostratigraphies for the eastern North European Plain.

Open research Europe·2026

Same author

What the landscape can tell: An integrative stratigraphic prospection approach to localize a Black Death mass grave in Erfurt/Central Germany.

PloS one·2026

Same author

Influence of PLIN5 and lipid composition on lipid droplet contact sites with other organelles.

Biochemistry and biophysics reports·2025

Same author

Exploring the gap between theory and experiment at the three-phase contact line of polystyrene droplets on soft PDMS.

Scientific reports·2025

Same author

Natural products chlorotonils exert a complex antibacterial mechanism and address multiple targets.

Cell chemical biology·2025

Same author

Deposit of Red Blood Cells at low concentrations in evaporating droplets is dominated by a central edge growth.

Journal of colloid and interface science·2024

Same journal

Tunable self-assembling cellular microarray for single-neutrophil vital and suicidal extracellular traps.

Lab on a chip·2026

Same journal

Precise programmable tumor cell subpopulation sorting <i>via</i> an electromagnetic microfluidic platform.

Lab on a chip·2026

Same journal

Bridging dimensions: combining one- and two-photon 3D printing for microfluidic device fabrication.

Lab on a chip·2026

Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026

Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026

Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 11, 2026

High Throughput Single-cell and Multiple-cell Micro-encapsulation

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

Flow field induced particle accumulation inside droplets in rectangular channels.

Michael Hein¹, Michael Moskopp, Ralf Seemann

¹Saarland University, Experimental Physics, Saarbrücken, Germany. r.seemann@physik.uni-saarland.de.

|June 3, 2015

Summary

This summary is machine-generated.

Field-free hydrodynamic accumulation of particles and cells in micro-droplets is achieved by manipulating droplet velocity. This method enables efficient particle concentration for biochemical assays and sample preparation.

More Related Videos

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Related Experiment Videos

Last Updated: Apr 11, 2026

High Throughput Single-cell and Multiple-cell Micro-encapsulation

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Capillary-based Centrifugal Microfluidic Device for Size-controllable Formation of Monodisperse Microdroplets

Published on: February 22, 2016

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Area of Science:

Biophysics
Microfluidics
Biochemical Engineering

Background:

Particle concentration is crucial for washing steps and enhancing analysis in biochemical assays.
Existing methods for particle concentration often require complex setups or external fields.
Microfluidic devices offer precise control over fluid dynamics for biological sample manipulation.

Purpose of the Study:

To present a novel method for field-free hydrodynamic particle and cell accumulation within droplets.
To investigate the influence of droplet velocity on particle distribution and accumulation patterns.
To demonstrate a technique for concentrating accumulated particles using droplet splitting.

Main Methods:

Utilizing rectangular micro-channels for droplet flow.
Manipulating droplet velocity to control particle sedimentation and internal flow fields.
Observing particle behavior through direct visualization within flowing droplets.
Employing a simple channel junction for droplet splitting and particle concentration.

Main Results:

Particles and cells accumulate at the rear of droplets or disperse based on droplet velocity.
Particle accumulation is governed by the interplay of sedimentation and the droplet's internal flow.
Changes in droplet shape with velocity alter the internal flow field and accumulation patterns.
Droplet splitting effectively concentrates accumulated particles, removing excess dispersed phase.

Conclusions:

Field-free hydrodynamic manipulation provides an efficient way to concentrate particles and cells in micro-droplets.
The method is tunable via droplet velocity, offering control over accumulation patterns.
This technique has significant potential for sample preparation in microfluidic biochemical assays.