Synchronization of the Estrous Cycle against the Background of Increased Excitability in Rats Selected for Catatonic
T A Alekhina1, D V Klochkov, N A Pal'chikova
1Laboratory of Evolutionary Genetics, Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russia, alek@bionet.nsc.ru.
Abstract:
Selection for the elevation of catatonic type of reaction in female GC rats ("genetic" and "catatonia") was followed by an increase in the number of intense running episodes in response to acoustic stimulation. The observed changes are typical of increased general excitability in these animals. The phenomenon of estrous cycle synchronization was confirmed by variations in the concentrations of estradiol and progesterone in groups of Wistar and GC rats differing by the degree of synchronization. Some differences were found in the concentration of main sex hormones in the blood from female GC and Wistar rats.
