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Adult-onset lymphoplasmacytic orchitis in a Labrador retriever stud dog.
Autumn P Davidson1, Benita J von Dehn2, Donald H Schlafer3
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA; Department of INternal Medicine, PetCare Veterinary Hospital East, Santa Rosa, CA, USA.
Topics in Companion Animal Medicine
|June 5, 2015
Summary
A formerly fertile Labrador retriever developed infertility due to autoimmune testicular disease. Histopathology confirmed an immune-mediated cause for azoospermia in this canine reproductive case.
Area of Science:
- Veterinary Medicine
- Canine Reproduction
- Immunology
Background:
- A 5-year-old, 45-kg Labrador retriever presented with azoospermia.
- The dog had a history of successful recent litters, indicating prior fertility.
Observation:
- Physical examination revealed bilaterally small and soft testes.
- Routine semen collection for artificial insemination identified the absence of sperm.
Findings:
- Excisional wedge biopsy of the testis was performed.
- Histopathology supported an immunologic, autoimmune pathogenesis.
Implications:
- The findings suggest autoimmune testicular disease as a cause of infertility in dogs.
- This highlights the importance of considering immune-mediated conditions in canine reproductive health evaluations.

