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[Comparative analysis of two main prognostic classifications for predicting the locally advanced prostate cancer
Objective:
comparison of two main clinical classifications D'Amico and NCCN for predicting the locally advanced prostate cancer. In this study we evaluated the preoperative data of 150 patients who underwent the radical prostatectomy. All patients were divided in prognostic groups according to NCCN and D'Amico classification criteria based on preoperative PSA level, digital rectal examination (DRE) and Gleason score. For comparative analysis of two main models statistical calculation was performed. Clinical application of magnetic resonance tomography is mandatory for evaluation of local extension for patients with intermediate and high risk. Comparative analysis of two main methods revealed the superiority of NCCN over D'Amico classification (p=0,0032) in predicting locally advanced prostate cancer.
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