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Unilateral corneal leukoplakia without limbal involvement
Koji Hirano1, Mihoko Koide2, Yoshikazu Mizoguchi3
1Department of Ophthalmology, Ban Buntane Hotokukai Hospital, School of Medicine, Fujita Health University, Nagoya, Japan.
International Medical Case Reports Journal
|June 10, 2015
Summary
Corneal leukoplakia, a white plaque on the eye, was successfully removed in a patient experiencing vision loss. Treatment for eyelid issues resolved the condition, restoring vision and preventing recurrence.
Area of Science:
- Ophthalmology
- Dermatology
- Pathology
Background:
- Leukoplakia typically affects oral mucosa but can present on the cornea.
- Unilateral corneal leukoplakia is rare and can impair vision.
Observation:
- A 26-year-old woman presented with a progressively expanding white corneal plaque.
- The condition affected pupillary area, causing vision impairment.
- Eyelid surgery for entropion led to a reduction in the corneal plaque size.
Findings:
- Histopathology confirmed leukoplakia with epidermal characteristics and hyperkeratosis.
- Surgical excision of the corneal plaque was complete.
- No recurrence was observed six months post-surgery, with visual acuity returning to normal.
Implications:
- Corneal leukoplakia may result from chronic ocular surface irritation, such as from eyelashes.
- Complete surgical removal can restore vision.
- Long-term monitoring is essential due to the potential for malignant transformation.
