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Updated: Apr 11, 2026

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea
Published on: February 21, 2016
Planar Pol(o)arity
Jakub Sedzinski1, John Wallingford2
1Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
Abstract:
Asymmetric localization of planar cell polarity (PCP) proteins is essential for tissue integrity, but how asymmetric localization is regulated during cell division is not known. In this issue of Developmental Cell, Shrestha et al. (2015) show that mitotic Polo-like kinase 1 (Plk1) links internalization of PCP proteins to cell-cycle progression.
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