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Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Introduction of an Integrated Pathology Image Management, Artificial Intelligence, and Reporting System

Published on: July 11, 2025

Advanced Imaging Techniques for the Pathologist.

Jeffrey L Fine¹

¹Subdivision of Advanced Imaging and Image Analysis (Pathology Informatics) Department of Pathology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

Surgical Pathology Clinics

|June 13, 2015

Summary

This summary is machine-generated.

Advanced imaging techniques like optical coherence tomography (OCT) offer promising diagnostic tools for pathology. However, they are unlikely to replace traditional hematoxylin-eosin (H&E) microscopy but will likely supplement it for targeted diagnoses.

Keywords:

Advanced imaging Digital pathology Ex vivo microscopy In vivo microscopy OCT Optical coherence tomography

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Area of Science:

Pathology
Medical Imaging
Biomedical Engineering

Background:

Traditional histopathology relies on hematoxylin-eosin (H&E) staining and microscopy.
Advanced imaging offers direct microscopic tissue visualization without H&E.
The integration of new imaging modalities into clinical practice is evolving.

Purpose of the Study:

To explore the role and potential of advanced imaging techniques in surgical pathology.
To present optical coherence tomography (OCT) as a specific example of advanced imaging.
To discuss the evolving relationship between surgical pathology and clinical patient care.

Main Methods:

Direct microscopic imaging of tissue.
Utilizing optical coherence tomography (OCT), an imaging technique based on reflected light.
Discussing practical experience and example images.

Main Results:

Advanced imaging techniques show diagnostic promise.
Optical coherence tomography (OCT) is presented as a key example.
These methods are unlikely to fully replace H&E histopathology.

Conclusions:

Advanced imaging, including OCT, is unlikely to supplant H&E histopathology.
OCT and similar technologies are expected to provide targeted diagnoses.
Applications include both in vivo (patient) and ex vivo (specimen) settings.