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Updated: Apr 9, 2026

Imaging of Biological Tissues by Desorption Electrospray Ionization Mass Spectrometry
Published on: July 12, 2013
Emitter-assigned multi-dielectric barrier-nano-electrospray ionization mass spectrometry
Irina Reginskaya1, Michael Schilling, Gökche Adali
1Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Bunsen-Kirchhoff-Str. 11, 44139, Dortmund, Germany.
Abstract:
A multi-dielectric-barrier-nano-electrospray ionization (multi-DB-nESI) emitter setup is presented where the emitters are quasi-simultaneously switched to ignite the respective spray solving the problem of coulombic interferences. Since the switching is done electronically, the sprays can be synchronized to the mass spectrometry (MS) ion trap and the resulting mass spectra can be assigned to the corresponding nESI emitter. Graphical Abstract Multi-dielectric-barrier-nano-electrospray in front of a mass spectrometer inlet.
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