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[Optic neuropathy induced by thinner sniffing].

K Kohriyama¹, H Hori, Y Murai

¹Department of Neurology, School of Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.

Journal of UOEH

|December 1, 1989

Summary

Thinner sniffing caused optic neuropathy and blindness in a teen. Methyl alcohol and methyl acetate in lacquer thinner were identified as the toxic solvents responsible for optic nerve damage.

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Area of Science:

Neuroscience
Toxicology
Ophthalmology

Background:

Substance abuse, specifically inhalant abuse, presents significant health risks.
Optic neuropathy is a serious condition affecting vision.

Observation:

A 17-year-old female presented with acute blindness and subsequent optic atrophy.
The patient reported a history of sniffing lacquer thinner for three months.
Brain CT scans showed symmetrical low attenuation in the bilateral putamen.

Findings:

Gas chromatography analysis identified methyl alcohol and methyl acetate as major components of the thinner.
These solvents were determined to be the cause of the optic neuropathy.
The case highlights the neurotoxic effects of inhalant abuse.

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Implications:

Accurate identification of solvents in cases of mixed organic solvent intoxication is crucial.
This case underscores the severe visual and neurological consequences of thinner sniffing.
Early diagnosis and intervention are vital for managing solvent-induced optic neuropathy.