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HLA Bw57 and DR7 association with psoriasis vulgaris in south India
R M Pitchappan1, A Koteeswaran, V N Kakkaniah
1Unit of Immunogenetics, School of Biological Sciences, Madurai Kamaraj University, India.
Tissue Antigens
|August 1, 1989
Abstract:
Eighty-three south Indian patients with psoriasis vulgaris were studied for HLA antigen frequencies and compared with 77 controls studied simultaneously. HLA Bw57, a split of B17 was found elevated in the patients. The two sexes differed in their age-at-onset curves: females had a preponderance to early onset of the disease, while the males had late onset. Among these patients, major group 3, a Western Brachycephal Armenoid group, revealed the highest risk for B17 & Bw57 but not major group 2, a Mediterranean one.