[DIETARY SUPPLEMENT REKECEN IMPROVES SAFETY AND EFFICACY OF CHRONIC PROSTATITIS ANTIBACTERIAL THERAPY]

Area of Science:

• Urology
• Microbiology
• Nutritional Science

Background:

• Chronic infectious prostatitis affects many patients, often requiring long-term treatment.
• Standard antibacterial therapy can have limitations and side effects.
• Novel therapeutic adjuncts are needed to improve treatment efficacy and patient outcomes.

Purpose of the Study:

• To evaluate the efficacy and safety of a natural complex of fermented food fibers and short-chain fatty acids (rekicen-RD®) as an adjunct to antibacterial therapy for chronic infectious prostatitis.
• To compare treatment outcomes between patients receiving standard therapy plus rekicen-RD® and those receiving standard therapy alone.

Main Methods:

• A randomized comparative study involving 64 patients with chronic infectious prostatitis.
• Patients were divided into two groups: a treatment group (antibacterial therapy + rekicen-RD®) and a control group (antibacterial therapy only).
• Efficacy was assessed using NIH-CPSI scores, quality of life, prostate echo-structure, and leukocytes in prostatic secretions at 8 weeks and 6 months.

Main Results:

• The addition of rekicen-RD® led to statistically significant improvements in all efficacy indicators compared to the control group.
• Long-term clinical efficacy reached 96.9%, with bacteriological efficacy at 87.5% (8 weeks) and 81% (6 months).
• The treatment group showed a 4.5-fold reduction in antibiotic-related adverse effects, with no gastrointestinal side effects reported.

Conclusions:

• Dietary supplement rekicen-RD® enhances the efficacy of antibacterial therapy for chronic infectious prostatitis.
• This natural complex improves clinical and bacteriological outcomes while reducing antibiotic-related side effects.
• Rekicen-RD® represents a safe and effective adjunctive treatment option for chronic prostatitis.