A Comprehensive Software and Database Management System for Glomerular Filtration Rate Estimation by Radionuclide...

Area of Science:

• Nephrology
• Medical Informatics
• Software Development

Background:

• Glomerular filtration rate (GFR) estimation is crucial for diagnosing kidney disease.
• Current GFR estimation methods, including plasma sampling (gold standard) and serum creatinine, have limitations such as complex calculations, lack of user-friendly software, and reliance on internet access.
• There is a need for accessible and efficient tools for accurate GFR assessment.

Purpose of the Study:

• To develop user-friendly software for estimating GFR using both plasma sampling and serum creatinine methods.
• To overcome the technical and computational barriers associated with traditional GFR estimation techniques.
• To provide a comprehensive tool for data storage and retrieval for future analysis.

Main Methods:

• Developed "GFR estimation software" using Microsoft Windows, Visual Basic 6.0, and Microsoft Access.
• Implemented Russell's formula for plasma sampling GFR calculation.
• Integrated MIRD, Cockcroft-Gault, Schwartz, and Counahan-Barratt methods for serum creatinine-based GFR estimation.

Main Results:

• The developed software accurately performs GFR calculations using multiple established formulas.
• The software is user-friendly, facilitating easy estimation of GFR by various methods.
• Enabled efficient storage and retrieval of patient data, raw data, and calculated GFR values.

Conclusions:

• The "GFR estimation software" provides a practical and user-friendly solution for accurate GFR assessment.
• The software enhances accessibility to gold-standard GFR estimation methods and improves routine clinical practice.
• It serves as a valuable system for managing and analyzing GFR-related data for research and clinical purposes.