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HIGH-RESOLUTION MULTIMODAL IMAGING AFTER IDIOPATHIC EPIRETINAL MEMBRANE SURGERY
Marco Lombardo1, Fabio Scarinci, Daniela Giannini
1*Fondazione G.B. Bietti IRCCS, Rome, Italy; †Department of Statistical Sciences, University of Rome "La Sapienza", Rome, Italy; ‡Azienda Ospedaliera San Giovanni Addolorata, Rome, Italy; §Consiglio Nazionale delle Ricerche, Istituto di Processi Chimico-Fisici (CNR-IPCF), Messina, Italy; and ¶Vision Engineering Italy srl, Rome, Italy.
Idiopathic epiretinal membrane (iERM) surgery alters the vitreomacular interface, reducing folds and changing hyperreflective structures. Adaptive optics imaging reveals these changes, aiding treatment outcome monitoring.
Area of Science:
- Ophthalmology
- Retinal Imaging
- Surgical Outcomes
Background:
- Idiopathic epiretinal membrane (iERM) affects the vitreomacular interface.
- Understanding post-surgical changes is crucial for patient outcomes.
Purpose of the Study:
- To investigate changes in the vitreomacular interface after iERM surgery over one year.
- To correlate adaptive optics (AO) and optical coherence tomography (OCT) findings.
Main Methods:
- Pilot study of six patients with fovea-attached iERM undergoing pars plana vitrectomy.
- AO and spectral domain OCT imaging pre- and post-surgery (1, 3, 6, 12 months).
- Inner limiting membrane removal in four cases using Brilliant blue G.
Main Results:
- Preoperatively, AO showed macrofolds, microfolds, and hyperreflective structures, defining radial and grid iERM types.
- Post-surgery, macrofolds and microfolds decreased; hyperreflective structures persisted with altered morphology.
- Differences observed between eyes with and without inner limiting membrane removal.
Conclusions:
- AO imaging provides novel insights into vitreomacular interface changes post-iERM surgery.
- Multimodal imaging is valuable for monitoring iERM treatment efficacy.
