Choroidal Involvement in Erdheim-Chester Disease

Area of Science:

• Ophthalmology
• Histiocytosis
• Rare Diseases

Background:

• Erdheim-Chester disease is a rare non-Langerhans cell histiocytosis affecting multiple organs.
• Commonly involves bone, CNS, and retroperitoneum; eye involvement is usually peri-orbital.

Observation:

• A 48-year-old presented with decreased vision in the left eye.
• Fundus examination revealed a macular choroidal mass.

Findings:

• This case represents potential choroidal involvement in Erdheim-Chester disease.
• This is believed to be the second reported case of its kind.

Implications:

• Highlights the importance of considering Erdheim-Chester disease in cases of unexplained choroidal masses.
• Suggests ophthalmological evaluation may be crucial for early diagnosis of Erdheim-Chester disease.
• Contributes to understanding the diverse manifestations of Erdheim-Chester disease.