Polycystic Ovary Syndrome and Central Serous Chorioretinopathy

The authors report a case series of five women with the diagnosis of polycystic ovary syndrome (PCOS) (n = 4) or a first-degree relative with PCOS (n = 1) who presented with central serous chorioretinopathy (CSR). This report is the first to correlate PCOS and CSR on clinical presentation. Patients with PCOS often exhibit physical evidence of elevated androgens, such as testosterone, which recently has been linked to CSR. The authors suggest that women with CSR be investigated for PCOS if indicated clinically. In addition, further studies should investigate the relationship between the two disorders.