Related Experiment Video
Updated: Apr 8, 2026

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
Published on: December 7, 2021
BlastXtract2: Improving early exploration of (meta) genomes
Heleen de Weerd1, Bernd E van der Veen2, Marcus J Claesson3
1Microbiology and Systems Biology, TNO, Zeist, The Netherlands.
Unlabelled:
To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required. Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences. Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic sequences.
Availability:
Source code, documentation and an online demo version are available at https://github.com/ ClaessonLab/BlastXtract2.
Related Concept Videos
Genomics
Evolutionary Relationships through Genome Comparisons
Genome Annotation and Assembly
Genetic Screens
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...
Genome Size and the Evolution of New Genes

