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Array Comparative Genomic Hybridization Array CGH for Detection of Genomic Copy Number Variants
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Published on: February 21, 2015

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CNVs in neuropsychiatric disorders.

George Kirov1

  • 1Cardiff University, MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, Hadyn Ellis Building, Cardiff CF24 4HQ, UK kirov@cardiff.ac.uk.

Human Molecular Genetics
|July 2, 2015
PubMed
Summary

Eleven copy number variations (CNVs) significantly elevate schizophrenia risk, affecting 2.4% of patients. These rare genetic variations also increase susceptibility to other neurodevelopmental disorders, impacting cognitive function even in unaffected individuals.

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