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Related Concept Videos

Mass Spectrometers01:16

Mass Spectrometers

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This lesson details the instrumentation of a mass spectrometer—a physical instrument to perform mass spectrometry on analyte molecules and record the characteristic mass spectra. This is achieved via three chief functions:
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Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation01:26

Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation

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Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy  (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
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Atomic Absorption Spectroscopy: Instrumentation01:22

Atomic Absorption Spectroscopy: Instrumentation

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An atomic absorption spectrophotometer (AAS) comprises several components: a radiation source, an atomizer, a monochromator, and a detector. The radiation source can be a hollow-cathode lamp (HCL) or an electrodeless-discharge lamp (EDL), both of which provide a narrow emission line of the required wavelength. However, some instruments use continuum sources and high-resolution monochromators to achieve a narrow range of radiation.
The atomizer used in AAS can be either a flame atomizer or an...
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Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview01:19

Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview

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In inductively coupled plasma–mass spectrometry (ICP–MS), an inductively coupled plasma (ICP) torch is used as an atomizer and ionizer. Solid samples are dissolved and volatilized before being introduced into the high-temperature argon plasma, while solution samples are nebulized and passed through the high-temperature argon plasma. Plasma dissociates the analytes and ionizes their component atoms to form a mixture of positive ions and molecular species. The positive ions are then...
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Instrument Calibration01:12

Instrument Calibration

1.3K
Instrument calibration is essential for ensuring that instruments produce accurate and consistent results. It is vital in manufacturing, healthcare, testing laboratories, and scientific research. Calibration processes are specific to each instrument and help enhance data accuracy. Each instrument has a unique calibration process tailored to its design and function to improve data accuracy.
Analytical Balance Calibration
An analytical balance measures mass and requires regular calibration to...
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Mass Spectrometry: Overview01:19

Mass Spectrometry: Overview

10.6K
Mass spectrometry is an analytical technique used to determine the molecular mass and molecular formula of a compound. The basic principle of mass spectrometry is to generate ions from the analyte molecule and measure these ion abundances against their molecular mass. One common type of ionization, known as electron ionization or EI, bombards the analyte molecules in the gas phase with high-energy electron beams. The electron beams displace an electron from the molecule and leave behind a...
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Related Experiment Video

Updated: Apr 7, 2026

Applications of the Single-probe: Mass Spectrometry Imaging and Single Cell Analysis under Ambient Conditions
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ChiMS: Open-source instrument control software platform on LabVIEW for imaging/depth profiling mass spectrometers.

Yang Cui1, Luke Hanley1

  • 1Department of Chemistry, University of Illinois at Chicago, Chicago, Illinois 60607, USA.

The Review of Scientific Instruments
|July 3, 2015
PubMed
Summary
This summary is machine-generated.

ChiMS is an open-source software for controlling mass spectrometers, enabling high-speed data acquisition, processing, and customized experiments for surface science and physical chemistry applications.

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Area of Science:

  • * Scientific instrumentation
  • * Analytical chemistry
  • * Surface science

Background:

  • * Mass spectrometry requires sophisticated control and data acquisition systems.
  • * Existing software may lack flexibility for specialized experiments.
  • * High-speed data handling is crucial for modern analytical techniques.

Purpose of the Study:

  • * To introduce ChiMS, an open-source software for mass spectrometry.
  • * To provide high-speed data acquisition and control capabilities.
  • * To facilitate customized experimental designs in various scientific fields.

Main Methods:

  • * Developed in LabVIEW for integration with mass spectrometers.
  • * Implements high-speed data transfer from digitizers to computer memory.
  • * Offers high-throughput data saving to hard disk and rapid data processing.
  • * Includes templates for user-designed experiments.

Main Results:

  • * ChiMS enables high-speed imaging and depth profiling for mass spectrometers.
  • * Efficient large dataset transfer and high-throughput data saving are achieved.
  • * Advanced data sorting and processing capabilities are integrated.
  • * Software supports customized experiments for diverse applications.

Conclusions:

  • * ChiMS provides a versatile and efficient solution for mass spectrometry data acquisition and control.
  • * The open-source nature fosters customization and broader application.
  • * Suitable for laser-based and non-laser based mass spectrometry, benefiting surface science and physical chemistry research.