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Updated: Apr 7, 2026

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
[Skin disorders in malignant hematologic diseases]
M Schmid-Wendtner1, T Hornung, M Meurer
1Interdisziplinäres Onkologisches Zentrum (IOZ) München, Nußbaumstr. 12, 80336, München, Deutschland, m.schmid-wendtner@ioz-muenchen.de.
Abstract:
Numerous cutaneous manifestations have been reported in patients with hematologic malignancies. This review provides an overview on this subject by dividing skin lesions into three main groups: (1) skin disorders due to vascular changes (dilatation, occlusion and inflammation), (2) unspecific (e.g. paleness, opportunistic infections) and specific skin lesions (e.g. leukemia cutis), and (3) the large group of paraneoplastic skin disorders. Emphasis is placed on clinical findings and therapeutic options of those paraneoplastic syndromes that are most frequently found in hematologic malignancies.
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