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Updated: Apr 7, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
Published on: November 5, 2016
Affinity-mediated capture and release of amphiphilic copolymers for controlling antimicrobial activity
Haruko Takahashi1, Kazunari Akiyoshi, Kenichi Kuroda
1Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48109, USA. kkuroda@umich.edu.
Abstract:
Capture and release of amphiphilic copolymers by a nano-sized polysaccharide gel (nanogel) was controlled by altering the hydrophobic binding affinity between the copolymer chains and nanogel. The antimicrobial activity of captured copolymer chains was suppressed, and regained upon release from the nanogel.
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