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Updated: Apr 7, 2026

Induction of Ocular Surface Inflammation and Collection of Involved Tissues
Published on: August 4, 2022
Ocular Surface as Barrier of Innate Immunity
Rodrigo Bolaños-Jiménez1, Alejandro Navas2, Erika Paulina López-Lizárraga3
1Research Unit, Institute of Ophthalmology, Conde de Valenciana Foundation, Chimalpopoca 14, Obrera, CP 06800, Mexico City, México ; Ophthalmology Department, Regional Hospital, Adolfo López Mateos, ISSSTE, México City, México.
Abstract:
Sight is one of the most important senses that human beings possess. The ocular system is a complex structure equipped with mechanisms that prevent or limit damage caused by physical, chemical, infectious and environmental factors. These mechanisms include a series of anatomical, cellular and humoral factors that have been a matter of study. The cornea is not only the most powerful and important lens of the optical system, but also, it has been involved in many other physiological and pathological processes apart from its refractive nature; the morphological and histological properties of the cornea have been thoroughly studied for the last fifty years; drawing attention in its molecular characteristics of immune response. This paper will review the anatomical and physiological aspects of the cornea, conjunctiva and lacrimal apparatus, as well as the innate immunity at the ocular surface.
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