Search for efficient complete and planned missing data designs for analysis of change
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Updated: Apr 7, 2026

Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
Published on: January 31, 2014
Wei Wu1, Fan Jia2, Mijke Rhemtulla3
1Department of Psychology, University of Kansas, 1415 Jayhawk Blvd., Lawrence, KS, 66044, USA. wwei@ku.edu.
Abstract:
The design of longitudinal data collection is an essential component of any study of change. A well-designed study will maximize the efficiency of statistical tests and minimize the cost of available resources (e.g., budget). Two families of designs have been used to collect longitudinal data: complete data (CD) and planned missing (PM) designs. This article proposes a systematic and flexible procedure named SEEDMC (SEarch for Efficient Designs using Monte Carlo Simulation) to search for efficient CD and PM designs for growth-curve modeling under budget constraints. This procedure allows researchers to identify efficient designs for multiple effects separately and simultaneously, and designs that are robust to MCAR attrition. SEEDMC is applied to identify efficient designs for key change parameters in linear and quadratic growth models. The identified efficient designs are summarized and the strengths and possible extensions of SEEDMC are discussed.
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