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Updated: Apr 7, 2026

Identification of Circular RNAs using RNA Sequencing
Published on: November 14, 2019
What happens at or after transcription: Insights into circRNA biogenesis and function
1a School of Life Sciences & CAS Key Laboratory of Brain Function and Disease; University of Science and Technology of China ; Hefei , Anhui Province , China.
Abstract:
Circular RNAs (circRNAs) are a large family of noncoding RNAs (ncRNAs) found in metazoans. Systematic studies of circRNAs have just begun. Here, we discuss circRNA biogenesis and functions with a focus on studies indicating great diversification of circRNAs. We highlight the recent identification of a special subtype of circRNAs, called EIciRNAs, and their role in transcriptional regulation. New insights on RNA-RNA interaction and other features associated with circRNA biology are also discussed.
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