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Published on: August 19, 2020
Evaluation and Management of Febrile, Well-appearing Young Infants
Eric A Biondi1, Carrie L Byington2
1Department of Pediatrics, University of Rochester Medical Center, 601 Elmwood Avenue, Box #667, Rochester, NY 14642, USA.
Insights
Managing febrile infants under 3 months presents a challenge. This review covers infection epidemiology, evidence-based diagnostics, and treatment to standardize care for these young patients.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neonatal Care
Background:
- Febrile infants under 3 months pose a diagnostic challenge.
- Varied clinical approaches exist for managing these infants.
- Standardized evidence-based guidelines are needed.
Purpose of the Study:
- To review the epidemiology of infections in febrile infants.
- To discuss evidence-based diagnostic and treatment strategies.
- To highlight variations in care and propose standardization.
Main Methods:
- Literature review of epidemiology.
- Analysis of diagnostic and treatment strategies.
- Examination of practice variations.
Main Results:
- Bacterial and viral infection epidemiology discussed.
- Evidence-based testing, admission, antibiotic, and discharge strategies presented.
- Significant variation in current care practices identified.
Conclusions:
- Standardizing care for febrile infants is crucial.
- Evidence-based strategies can improve management.
- Further research may refine best practices.
Abstract:
The evaluation and management of well-appearing febrile infants less than 3 months of age has presented a decades-long clinical conundrum for providers. This article reviews the epidemiology of bacterial and viral infections in these infants. It discusses evidence-based diagnostic and treatment strategies, including appropriate use of testing, admission to the hospital, use of antibiotics, and hospital discharge. It also highlights the substantial variation in care for febrile infants and provides strategies to standardize practice.
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