Aldosterone Synthase Promoter Polymorphism and Cardiovascular Phenotypes in a Large, Multiethnic Population-Based

James Brian Byrd1, Richard J Auchus, Perrin C White

  • 1From the*University of Michigan, Ann Arbor, MI; and †University of Texas Southwestern Medical Center, Dallas, TX.

Summary

This study found no association between the CYP11B2 gene variant -344C/T and cardiovascular risk factors like blood pressure or aldosterone levels in a large, multiethnic cohort. Previous findings could not be replicated, suggesting methodological differences may be at play.

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