A novel visible light mediated radical cyclization of enol lactones: a concise method for fluorinated polycyclic
Chuanhua Qu1, Pan Xu, Wujiang Ma
1State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, P. R. China. cjzhu@nju.edu.cn.
Chemical Communications (Cambridge, England)
|July 29, 2015
Abstract:
A novel visible light mediated radical cyclization of enol lactones with difluoroacyl arenes is presented. The reaction experienced a tandem radical cyclization and tolerated a wide range of substrates, resulting in fluorinated γ-butyrolactones in good chemical yield and with excellent diastereoselectivity.
