Related Experiment Video
Updated: Apr 6, 2026

08:41
Mouse Round Spermatid Injection
Published on: January 26, 2024
1.7K
Infertility with Testicular Cancer
Kevin A Ostrowski1, Thomas J Walsh2
1Department of Urology, Oregon Health and Science University, 3303 Southwest Bond Avenue, CH10U, Portland, OR 97239, USA.
The Urologic Clinics of North America
|July 29, 2015
Summary
Testicular cancer is highly curable, but treatments can cause infertility. This review examines infertility risks and fertility preservation options for cancer survivors.
Area of Science:
- Oncology
- Reproductive Medicine
- Cancer Survivorship
Background:
- Testicular germ cell cancer is a highly curable malignancy.
- Treatment often occurs during the reproductive years, posing a risk to fertility.
- Infertility is a significant concern impacting quality of life for survivors.
Purpose of the Study:
- To review factors contributing to infertility in testicular cancer patients.
- To assess specific fertility risks associated with various cancer treatments.
- To discuss optimal timing for fertility discussions and available preservation options.
Main Methods:
- Focused literature review.
- Analysis of factors influencing male infertility post-cancer treatment.
- Evaluation of current fertility preservation techniques.
Main Results:
- Various testicular cancer treatments carry distinct fertility risks.
- Early discussion of fertility preservation is crucial.
- Several fertility treatment options are available for survivors.
Conclusions:
- Understanding and addressing infertility is vital for testicular cancer patient quality of life.
- Proactive fertility management should be integrated into cancer care.
- Survivors have options for fertility preservation and treatment.
Related Concept Videos
Infertility in Males
685
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
685
Disorders of the Male Reproductive System
5.5K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.5K
Spermatogenesis
124.8K
Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male...
124.8K
Spermatogenesis
11.1K
Spermatogenesis is a complex process that involves the development of sperm cells from undifferentiated stem cells in the seminiferous tubules of the testes. The process is essential for the production of mature and functional sperm cells that are capable of fertilizing an egg.
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
The process of spermatogenesis can be divided into mitosis, meiosis, and spermiogenesis. During mitosis, the spermatogonia or stem cells divide to produce two identical daughter cells, type A and B spermatogonia. Type-A...
11.1K
Testes: Histology
3.8K
A tough, fibrous membrane, the tunica albuginea, covers the testes, extending inward to form fibrous partitions or septa, dividing them into internal compartments called lobules. Each lobule has 1 to 3 tightly coiled seminiferous tubules where sperm production occurs. These tubules merge into a tubular network at the back of the testis, known as the rete testis. It connects to 15 to 20 efferent ductules, leading to the epididymis.
The spermatogenic cells, responsible for producing sperm, are...
The spermatogenic cells, responsible for producing sperm, are...
3.8K
Infertility in Females
5.0K
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
5.0K

