Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Map of spiking activity underlying change detection in the mouse visual system.

Cell·2026
Same author

Pupil-DLC: An open-source deep learning pipeline for scalable, marker-less tracking of pupil dynamics across conscious and unconscious states.

Journal of neuroscience methods·2026
Same author

Sleep lowers waking theta frequency in the rat hippocampus.

Cell reports·2026
Same author

Neuropixels Opto: combining high-resolution electrophysiology and optogenetics.

Nature methods·2026
Same author

The Role of Plasticity in Replay: Stability Through Anti-Hebbian Rules.

Hippocampus·2026
Same author

Rapid formation of non-spatial hippocampal representations consistent with behavioral timescale synaptic plasticity is modulated by entorhinal input.

Nature communications·2026

Related Experiment Video

Updated: Apr 5, 2026

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice
07:10

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice

Published on: July 1, 2018

9.5K

Local Field Potentials Encode Place Cell Ensemble Activation during Hippocampal Sharp Wave Ripples.

Jiannis Taxidis1, Costas A Anastassiou2, Kamran Diba3

  • 1Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

Neuron
|August 7, 2015
PubMed
Summary

Local field potential (LFP) amplitudes encode the activation of place cell ensembles during in vivo replays. This finding offers a new method for detecting structured population activity using LFP signals.

More Related Videos

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit
11:37

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Published on: August 2, 2017

10.4K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

6.2K

Related Experiment Videos

Last Updated: Apr 5, 2026

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice
07:10

Recording Spatially Restricted Oscillations in the Hippocampus of Behaving Mice

Published on: July 1, 2018

9.5K
Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit
11:37

Tuning in the Hippocampal Theta Band In Vitro: Methodologies for Recording from the Isolated Rodent Septohippocampal Circuit

Published on: August 2, 2017

10.4K
Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology
09:44

Author Spotlight: Advancing Large-Scale Neural Dynamics Through HD-MEA Technology

Published on: March 8, 2024

6.2K

Area of Science:

  • Neuroscience
  • Computational Neuroscience
  • Electrophysiology

Background:

  • The encoding of spiking cell ensemble activation within the local field potential (LFP) is not fully understood.
  • Investigating neural population activity during sharp wave ripples is crucial for understanding memory consolidation.

Purpose of the Study:

  • To determine if local field potential (LFP) signals can encode the activation of spiking cell ensembles during in vivo replays.
  • To explore the relationship between place cell sequence spiking and LFP characteristics in the rat hippocampus.

Main Methods:

  • In vivo electrophysiological recordings in the rat hippocampus.
  • Realistic biophysical modeling of neural activity.
  • Analysis of local field potential (LFP) signals during sharp wave ripples and sequence replays.

Main Results:

  • Multi-site perisomatic LFP amplitudes (150-200 Hz) reliably reflect spatial constellations of spiking cells.
  • LFP signals encode the activation of local place cell ensembles during in vivo replays.
  • Consistent spatiotemporal LFP patterns correlate with ordered place cell ensemble activation, enabling efficient segregation of replay events.

Conclusions:

  • Extracellular encoding of spatiotemporal ensemble spiking is demonstrated via LFP.
  • This provides a method for efficient, LFP-based detection and monitoring of structured population activity in vivo.
  • The findings enhance our understanding of neural population coding and memory processes.