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Sarcoidosis. Debut as orbital pseudotumour
P Rocha Cabrera1, J A Abreu Reyes2, J Fernández Ramos3
1Servicio de Oftalmología, Hospital San Juan de Dios, Tenerife, España; Servicio de Oftalmología, Hospital Universitario de Canarias, Tenerife, España.
Archivos De La Sociedad Espanola De Oftalmologia
|August 10, 2015
Summary
Orbital sarcoidosis, a rare inflammatory condition, can mimic orbital pseudotumor. This case report highlights non-caseating granulomas as key diagnostic findings, successfully treated with corticosteroids and methotrexate.
Area of Science:
- Ophthalmology
- Rheumatology
- Pathology
Background:
- Orbital pseudotumor is a diagnosis of exclusion, presenting with diverse orbital inflammatory signs.
- Sarcoidosis is a multisystem granulomatous disease that can affect the orbit, mimicking other orbital pathologies.
Observation:
- A 78-year-old female presented with acute onset left orbital pseudotumor symptoms including proptosis, pain, periorbital edema, and ptosis.
- MRI revealed an orbital mass and lacrimal gland involvement, suggestive of an orbital tumor or inflammatory process.
Findings:
- Histopathology of an eyelid lesion confirmed non-caseating granulomas, the hallmark of sarcoidosis.
- The patient was diagnosed with orbital sarcoidosis based on clinical, imaging, and pathological findings.
Implications:
- This case underscores the importance of considering sarcoidosis in the differential diagnosis of orbital pseudotumor.
- Systemic corticosteroid and methotrexate therapy effectively controlled the orbital inflammation in this patient, suggesting a favorable treatment response for this condition.
