Related Experiment Video
Updated: Apr 5, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
Published on: November 1, 2024
The Relationship Between Helicobacter pylori Infection and Open-Angle Glaucoma: A Meta-Analysis
Purpose:
Previous studies assessed the associations between Helicobacter pylori infection and open-angle glaucoma (OAG) and produced inconsistent results. Therefore, we performed a meta-analysis to evaluate the effects of H. pylori infection on OAG risk.
Methods:
Relevant studies that reported the associations between H. pylori infection and OAG were identified through an extensive search of the Exerpta Medica Database (EMBASE), Web of Science, and PubMed databases in English and Chinese National Knowledge Infrastructure, VIP, and Wan Fang databases in Chinese, and by reviewing the reference lists of the key articles. The summary odds ratio (OR) and 95% confidence interval (CI) were calculated using the random-effects model.
Results:
This meta-analysis involved 695 glaucoma patients and 1580 control individuals. The overall combined ORs showed a significant correlation between H. pylori infection and OAG (OR = 2.08, 95% CI = 1.42-3.04). The subgroup analysis showed the association of H. pylori infection with primary open-angle glaucoma (POAG; OR = 3.06, 95% CI = 1.27-2.46) and normal tension glaucoma (NTG; OR = 1.77, 95% CI = 1.76-5.34), but not with pseudoexfoliation glaucoma (PXFG; OR = 1.46, 95% CI = 0.40-5.30).
Conclusions:
The result of this meta-analysis suggested a statistically significant association between H. pylori infection and OAG. Further analysis showed that this positive relation is observed only in POAG and NTG patients, but not in the PXFG patients.
More Related Videos
05:13Rapid Detection of Helicobacter pylori Virulence and Typing Using Quantum Dot Labeling Technology
Published on: June 13, 2025
09:05High Resolution Electron Microscopy of the Helicobacter pylori Cag Type IV Secretion System Pili Produced in Varying Conditions of Iron Availability
Published on: November 21, 2014
Related Concept Videos
Glaucoma: Overview
Peptic Ulcer
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy