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Updated: Apr 5, 2026

05:51
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
Published on: July 24, 2016
20.7K
[VARICELLA ZOSTER VIRUS AND DISEASES OF CENTRAL NERVOUS SYSTEM VESSELS]
Summary
Varicella Zoster virus (VZV) can cause VZV-vasculopathy, affecting central nervous system arteries. Vaccine prophylaxis for chickenpox and herpes zoster may influence VZV-vasculopathy development and severity.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Medicine
Context:
- Varicella Zoster virus (VZV) is a significant pathogen with neurological implications.
- VZV-vasculopathy, a form of central nervous system (CNS) artery damage, requires comprehensive understanding.
- The review synthesizes current knowledge on VZV-vasculopathy.
Purpose:
- To systematically review the epidemiology, pathogenesis, clinical manifestations, diagnostics, and therapy of VZV-vasculopathy.
- To highlight the impact of VZV infection on CNS vasculature.
- To evaluate the role of vaccine prophylaxis in managing VZV-vasculopathy.
Summary:
- Presents systematized data on VZV-vasculopathy, detailing its occurrence from VZV damage to CNS arteries.
- Discusses epidemiology, pathogenesis, clinical presentation, diagnostic methods, and therapeutic strategies.
- Emphasizes the influence of chickenpox and herpes zoster vaccine prophylaxis on disease frequency and progression.
Impact:
- Provides a consolidated resource for clinicians and researchers on VZV-vasculopathy.
- Informs clinical practice regarding diagnosis and treatment of VZV-related CNS vasculitis.
- Underscores the potential preventive role of VZV vaccination in reducing vasculopathy incidence and severity.
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