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Updated: Apr 5, 2026
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A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
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Clinically-indicated replacement versus routine replacement of peripheral venous catheters
Joan Webster1, Sonya Osborne, Claire M Rickard
1Centre for Clinical Nursing, Royal Brisbane and Women's Hospital, Level 2, Building 34, Butterfield Street, Brisbane, Queensland, Australia, 4029.
The Cochrane Database of Systematic Reviews
|August 15, 2015
Summary
Routine replacement of peripheral intravenous (IV) catheters is not supported by evidence. Changing IV catheters only when clinically indicated reduces costs and patient discomfort without increasing infection or phlebitis risks.
Area of Science:
- Evidence-based medicine
- Infection control
- Vascular access devices
Background:
- Current guidelines recommend routine peripheral intravenous (IV) catheter replacement every 72-96 hours to prevent complications.
- Routine replacement incurs costs and patient discomfort, potentially unnecessarily.
- This review updates previous findings on IV catheter management strategies.
Purpose of the Study:
- To compare the outcomes of removing peripheral IV catheters based on clinical need versus routine replacement.
- To evaluate the impact on infection rates, phlebitis, and costs.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials.
- Searched major databases including Cochrane Vascular Specialised Register and CENTRAL.
- Included trials comparing clinically indicated removal versus routine replacement in hospitalized or community patients.
Main Results:
- Seven trials involving 4895 patients were analyzed. High-quality evidence showed no significant difference in catheter-related bloodstream infection (CRBSI) or phlebitis rates between groups.
- Clinically indicated removal resulted in significant cost savings (approximately AUD 7.00 per patient).
- All-cause bloodstream infection rates were also similar between the clinically indicated and routine replacement groups.
Conclusions:
- There is no evidence to support the routine 72-96 hour replacement of peripheral IV catheters.
- Healthcare organizations should consider adopting policies for clinically indicated catheter removal.
- This approach reduces patient pain and healthcare costs while maintaining safety.
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