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Calcium signaling and cell proliferation.

Mauro Cunha Xavier Pinto1, Alexandre Hiroaki Kihara2, Vânia A M Goulart3

  • 1Departamento de Bioquímica e Imunologia, Instituto de Ciência Biológicas, Univtreersidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901 Belo Horizonte, MG, Brazil; Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Presyes 748, 05508-000 São Paulo, SP, Brazil; Instituto Nanocell, Rua Santo Antônio, 420, 35500-041 Divinópolis, MG, Brazil.

Cellular Signalling
|August 16, 2015
PubMed
Summary

Calcium signaling regulates cell proliferation. Store-operated calcium entries (SOCE), involving STIM and Orai proteins, are crucial for this process, linking endoplasmic reticulum calcium levels to cellular calcium influx and proliferation.

Keywords:
CRACCa(2+) signalingCalcium channelsOrai1SOCESTIMcell proliferation

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