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Updated: Apr 5, 2026

A Polyaniline-based Sensor of Nucleic Acids
Published on: November 1, 2016
A novel detection technique of polyamide binding sites by photo-induced electron transfer in (Br)U substituted DNA
Abhijit Saha1, Fumitaka Hashiya, Seiichiro Kizaki
1Department of Science, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8501, Japan. hs@kuchem.kyoto-u.ac.jp.
Abstract:
We report the photochemistry of (Br)U substituted DNA as a versatile platform to investigate the binding sites of pyrene conjugated pyrrole imidazole polyamides (PIPs). The results suggest that the approach can be used on a routine basis for the screening of polyamide binding sites.
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