[The dynamic activity of the hepatic interstitial volume receptors under conditions of varying stimulation]

The activity of single functional units with interstitial and vasal-interstitial patterns of discharge were studied in different kinds of stimulation: repeated infusions of saline with 10-min. intervals or continuous long-term infusions of hypertonic sodium chloride solutions into the portal vein, during and after acute block of hepatic venous outflow. The former infusions potentiated responses of these units. The long-term infusions of hypertonic NaCl solutions led to durable responses with a delayed onset and/or maximal manifestation. The data obtained suggests a major role of these receptors in the sodium balance control under normal and pathological conditions.