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Multiple Infectious Complications in a Severely Injured Patient with Single Nucleotide Polymorphisms in Important

Maarten W G A Bronkhorst1, Peter Patka2, Esther M M Van Lieshout1

  • 1Trauma Research Unit Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

The Open Orthopaedics Journal
|August 28, 2015
PubMed
Summary

Genetic variations in innate immune genes like MBL2 and TLR2 may increase susceptibility to severe infections after trauma. This case highlights how polymorphisms contribute to infectious complications and prolonged hospital stays in trauma patients.

Keywords:
Complicationsgenetic variationinfectionmultiple organ dysfunction syndromesingle nucleotide polymorphismsystemic inflammatory response syndrometrauma.

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