Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

6.2K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
6.2K
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.7K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.7K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

921
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
921
Disorders of Hemostasis01:24

Disorders of Hemostasis

2.8K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
2.8K
Disorders of Leukocytes01:27

Disorders of Leukocytes

2.4K
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune...
2.4K
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

4.2K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hermansky-Pudlak Syndrome Complicated by Crohn's Disease and Hidradenitis Suppurativa: A Case of Multisystem Immune Dysregulation.

ACG case reports journal·2025
Same author

Cosmeceuticals in the Pediatric Population Part II: Ethical Dilemmas and Patient Talking Points.

Pediatric dermatology·2025
Same author

Cosmeceuticals in the Pediatric Population Part I: A Review of Risks and Available Evidence.

Pediatric dermatology·2025
Same author

Profiling <i>PIK3CA</i> variants in disorders of somatic mosaicism.

Genetics in medicine open·2024
Same author

Neonatal Miliaria Pustulosa-A Case Series.

Pediatric dermatology·2024
Same author

Malassezia-associated skin diseases in the pediatric population.

Pediatric dermatology·2024
Same journal

Centering Lived Experience: Inclusive Pediatric Care for Children Who Are Deaf and Hard of Hearing and Their Families.

Pediatric annals·2026
Same journal

From Early Childhood to Adulthood: Implementing Neuroaffirming Health Care for Autistic Individuals.

Pediatric annals·2026
Same journal

Neurodivergence in Medical Education: Current Landscape and Inclusive Future for Pediatrics.

Pediatric annals·2026
Same journal

Neurodiversity and Intellectual Disability: Opportunities and Challenges for Functioning and Participation Across the Life Course.

Pediatric annals·2026
Same journal

Action for Access: Equity for Children With Disabilities in Lowand Middle-Income Countries.

Pediatric annals·2026
Same journal

Rethinking "Healthy" for Every Child: Building Flexible, Family Centered Routines in a Neurodiverse World.

Pediatric annals·2026
See all related articles

Related Experiment Video

Updated: Apr 4, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

11.0K

Blistering Disorders in Children.

Duri Yun, Sarah L Stein

    Pediatric Annals
    |August 28, 2015
    PubMed
    Summary
    This summary is machine-generated.

    Pediatric bullous disorders present diagnostic challenges, ranging from mild to life-threatening. This review aids in differentiating common acquired blistering conditions in children through careful evaluation.

    More Related Videos

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
    11:17

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

    Published on: August 11, 2018

    12.7K
    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
    07:22

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

    Published on: March 14, 2025

    1.4K

    Related Experiment Videos

    Last Updated: Apr 4, 2026

    Granulocyte-dependent Autoantibody-induced Skin Blistering
    12:23

    Granulocyte-dependent Autoantibody-induced Skin Blistering

    Published on: October 12, 2012

    11.0K
    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
    11:17

    A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo

    Published on: August 11, 2018

    12.7K
    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
    07:22

    A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis

    Published on: March 14, 2025

    1.4K

    Area of Science:

    • Pediatric Dermatology
    • Immunodermatology
    • Clinical Pathology

    Background:

    • Bullous disorders in children represent a diverse group of conditions with varied etiologies, including inherited and acquired causes.
    • Common acquired forms encompass allergic reactions, infections, autoimmune processes, and toxin-mediated conditions, posing diagnostic challenges.

    Observation:

    • Clinical presentation of pediatric bullous disorders can range from self-limited eruptions to severe, life-threatening conditions.
    • Diagnostic approaches involve meticulous history taking, detailed morphologic examination of skin lesions, and judicious use of skin scrapings, biopsies, and cultures.

    Findings:

    • This review focuses on commonly encountered acquired bullous eruptions in pediatric patients.
    • Key differentiating features and diagnostic strategies for these conditions are discussed.

    Implications:

    • Accurate diagnosis of pediatric bullous disorders relies on understanding pathophysiology and employing appropriate diagnostic tools.
    • Effective differentiation aids in timely and appropriate management, impacting patient outcomes.