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Updated: Apr 4, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Biomolecular DNP-Supported NMR Spectroscopy using Site-Directed Spin Labeling.

Elwin A W van der Cruijsen1, Eline J Koers1, Claire Sauvée2

  • 1NMR research group Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, 3584 CH Utrecht (The Netherlands).

Chemistry (Weinheim an Der Bergstrasse, Germany)
|August 29, 2015
PubMed
Summary

Chemical labeling with radicals enhances Nuclear Magnetic Resonance (NMR) sensitivity for complex molecules. This approach improves site-specificity and resolution in Dynamic Nuclear Polarization (DNP) studies.

Keywords:
DNPKcsAMTSSLNMR spectroscopymembrane proteinsspin labeling

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