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Updated: Apr 4, 2026
08:31
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Published on: September 20, 2021
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Herpes Zoster Ophthalmicus
Julie L Johnson1, Rianot Amzat1, Nicolle Martin1
1Department of Family and Preventive Medicine, Emory University School of Medicine, 4500 North Shallowford Road, Suite B, Atlanta, GA 30338, USA.
Primary Care
|August 31, 2015
Summary
Herpes zoster, or shingles, affects about 1 million Americans yearly. Vaccination and early treatment with antivirals are key for managing this common viral infection, especially for high-risk groups.
Area of Science:
- Virology
- Epidemiology
- Dermatology
Background:
- Herpes zoster (shingles) is a common viral disorder with an estimated 1 million new cases annually in the US.
- The incidence rate is approximately 3.2 per 1000 person-years.
- Patients with HIV face a significantly higher risk of herpes zoster ophthalmicus.
Purpose of the Study:
- To outline the epidemiology and risk factors for herpes zoster.
- To discuss primary prevention strategies, including vaccination.
- To detail current treatment and management approaches for herpes zoster.
Main Methods:
- Literature review of epidemiological data on herpes zoster incidence and risk factors.
- Summary of established prevention modalities, focusing on vaccination.
- Overview of therapeutic interventions, including pharmacological and multidisciplinary approaches.
Main Results:
- Herpes zoster affects approximately 1 million individuals in the US each year.
- Key risk factors include HIV infection, advanced age, immunosuppression, and early life primary varicella-zoster virus infection.
- Vaccination is a primary prevention method.
Conclusions:
- Herpes zoster is a prevalent condition requiring comprehensive management strategies.
- Early intervention with antivirals, analgesics, and anticonvulsants is crucial.
- Multidisciplinary care involving various specialists may be necessary for optimal patient outcomes.
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