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Sudden Death in a Case of Isolated Left Ventricular Noncompaction: An Autopsy Case Report
Shilpa K Lad1, Gayathri Amonkar
1From the Department of Pathology, Topiwala National Medical College and BYL Nair Charitable Hospital, Mumbai, Maharashtra, India.
The American Journal of Forensic Medicine and Pathology
|September 3, 2015
Summary
Isolated left ventricular noncompaction, a rare heart muscle disorder, can lead to sudden death. This case highlights the risk in adolescents without prior cardiac history.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Genetics
Background:
- Left ventricular noncompaction (LVNC) is a congenital cardiomyopathy characterized by excessive trabeculations and deep intertrabecular recesses.
- It is often associated with other congenital heart defects, but can occur in isolation.
Observation:
- A 15-year-old female presented with sudden cardiac death.
- Autopsy revealed isolated left ventricular noncompaction without any other cardiac anomalies or a history of heart disease.
Findings:
- The case demonstrates that isolated left ventricular noncompaction can be the sole cardiac abnormality leading to sudden death in an adolescent.
- Histopathological examination confirmed the diagnosis of noncompaction of the left ventricle.
Implications:
- This case underscores the importance of considering rare cardiomyopathies in the differential diagnosis of sudden death in young individuals.
- Early recognition and diagnosis of left ventricular noncompaction are crucial for risk stratification and management, even in the absence of typical risk factors.
