Related Experiment Video
Updated: Mar 31, 2026

08:10
Diagnosing Pulmonary Tuberculosis with the Xpert MTB/RIF Test
Published on: April 9, 2012
82.3K
Pancardiac tuberculosis - a case report
Shilpa K Lad1, Gayathri Amonkar1
1Department of Pathology, TNMC and BYL Nair Ch. Hospital, Mumbai, 400 008.
Summary
Tuberculosis of the heart is rare, but this case details extensive involvement of all cardiac layers in a 14-year-old female. This highlights the potential for widespread cardiac tuberculosis, even in young patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Pathology
Background:
- Tuberculosis (TB) is a significant global health issue.
- Cardiac tuberculosis is an uncommon manifestation of TB.
- Previous reports indicate TB predominantly affects the pericardium and myocardium, with rare endocardial involvement.
Observation:
- A 14-year-old female presented with symptoms suggestive of cardiac compromise.
- Diagnostic investigations revealed extensive tuberculous involvement.
- The disease affected all layers of the heart: pericardium, myocardium, and endocardium.
Findings:
- The case demonstrates florid and widespread tuberculous infiltration of the entire heart.
- This represents a rare instance of endocardial tuberculosis alongside pericardial and myocardial disease.
- Histopathological examination confirmed active caseating granulomas consistent with tuberculosis.
Implications:
- This case underscores the importance of considering cardiac tuberculosis in the differential diagnosis of unexplained cardiac conditions, especially in endemic areas.
- Extensive cardiac TB, including endocardial involvement, can present a diagnostic and therapeutic challenge.
- Further research into the pathogenesis and management of widespread cardiac tuberculosis is warranted.
Related Concept Videos
Pulmonary Tuberculosis I
1.4K
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
1.4K
Pulmonary Tuberculosis V
864
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
864
Pulmonary Tuberculosis II
2.1K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
2.1K
Pulmonary Tuberculosis III
1.4K
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
The first classification is based on the development of the disease, and it includes the following categories:
1.4K
Pulmonary Tuberculosis IV
704
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
704
Endocarditis I: Introduction
760
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
760
