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Odontogenic and rhinogenic chronic sinusitis: a modern microbiological comparison
Alberto Maria Saibene1, Christian Vassena2, Carlotta Pipolo1
1Department of Otolaryngology-Head and Neck, San Paolo Hospital, University of Milan, Milan, Italy.
International Forum of Allergy & Rhinology
|September 9, 2015
Summary
Odontogenic sinusitis (SCDDT) shows higher microbial contamination than rhinogenic sinusitis. Findings suggest tailored treatments are necessary for SCDDT patients due to distinct etiopathogenesis and microbiology.
Area of Science:
- Otorhinolaryngology
- Microbiology
- Infectious Diseases
Background:
- Odontogenic sinusitis and sinonasal complications of dental disease or treatment (SCDDT) are significant causes of paranasal sinus infections.
- SCDDT requires distinct treatment strategies compared to rhinogenic sinusitis due to differing etiopathogenesis.
- This study investigates the microbiology and antibiotic resistance in SCDDT patients.
Purpose of the Study:
- To comprehensively evaluate the microbiology and antibiotic resistance patterns in patients with SCDDT.
- To compare these findings with a control group of patients suffering from rhinogenic sinusitis.
Main Methods:
- Surgical microbiological sampling was performed on 28 SCDDT patients and 16 chronic rhinosinusitis with nasal polyps (CRSwNP) patients.
- Bacterial identification was achieved through classic biochemical methods and confirmed by DNA pyrosequencing.
- Antibiotic resistance profiles of SCDDT isolates were determined.
Main Results:
- Microbial growth was detected in all SCDDT patients, unlike 60% of the control group (p < 0.001).
- Anaerobic growth was observed in 14% of SCDDT patients versus 7% of CRSwNP patients (p = 0.42).
- SCDDT isolates showed 70% susceptibility to amoxicillin/clavulanate, 100% to levofloxacin, teicoplanin, and vancomycin; 80% of staphylococci produced beta-lactamase.
Conclusions:
- SCDDT involves extensive microbial contamination in the maxillary sinus, differentiating it from rhinogenic sinusitis.
- These findings underscore the necessity for specialized treatment approaches for SCDDT.
- Further research into targeted therapies for SCDDT is warranted.
Keywords:
bacteriologychronic diseasechronic rhinosinusitisfungal sinusitismedical therapy of chronic rhinosinusitisparanasal sinus diseasesrhinosinusitisMore Related Videos
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