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Updated: Aug 7, 2026

Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis
Published on: July 4, 2007
[Neurolues--clinical characteristics, diagnosis and therapy]
Abstract:
A female patient with neurolues was presented in this paper. The disease started 25 years after primoinfection by neurologic disturbances which corresponded to classic neurolues with the signs of meningovascular and parenchymatous disease. The diagnosis was confirmed by positive serologic tests, computerized brain tomography--whereby syphilomas were found in the brain and by histopathologic survey of one of peripheral syphilomas. Antibiotic therapy with high penicillin doses was initiated but without more significant clinical effects, it only led to negativization of serologic tests. The patient died after two months. Serologic tests to syphilis should be temporarily repeated in all patients suspective of neurolues, in order to initiate or repeat the previously employed therapy.
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