Current treatment of hypertension in patients with coronary artery disease recommended by different guidelines
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1a New York Medical College, Westchester Medical Center, Cardiology Division, Department of Medicine , Macy Pavilion, Room 148, Valhalla 10595, NY, USA +1 91 44 93 53 11 ; +1 91 42 35 62 74 ; wsaronow@aol.com.
Insights
Treating hypertension in patients with coronary artery disease (CAD) involves beta blockers and ACE inhibitors or ARBs. Long-acting nitrates are also key, with calcium-channel blockers added if needed. Target blood pressure is <140/90 mmHg for those under 80.
Area of Science:
- Cardiology
- Hypertension Management
- Coronary Artery Disease Treatment
Background:
- Effective management of hypertension is crucial for patients with coronary artery disease (CAD).
- Current treatment strategies require updates based on evolving clinical guidelines.
- The 2015 American Heart Association/American College of Cardiology/American Society of Hypertension guidelines provide updated recommendations.
Purpose of the Study:
- To review and update treatment protocols for hypertension in patients diagnosed with CAD.
- To discuss the implications of the 2015 hypertension guidelines for CAD patient care.
Main Methods:
- A comprehensive literature search was conducted using Medline.
- Studies published between 1968 and 2015 were reviewed for treatment of hypertension in CAD patients.
- Data from 1977 to 2015 were specifically reported.
Main Results:
- Beta blockers combined with ACE inhibitors or ARBs are recommended for hypertension in CAD.
- Long-acting nitrates demonstrate efficacy in managing angina and ischemia.
- Calcium-channel blockers (CCBs) can be utilized as an adjunct therapy if angina persists.
Conclusions:
- The recommended treatment for hypertension in CAD patients includes beta blockers and ACE inhibitors or ARBs.
- Long-acting nitrates are effective for antianginal and anti-ischemic effects.
- CCBs are indicated for persistent angina despite optimal beta blocker and nitrate therapy.
- Blood pressure targets are <140/90 mmHg for patients ≤80 years and <150 mmHg systolic for patients ≥80 years.
Introduction:
It is important to know how to treat hypertension in patients with coronary artery disease (CAD). The reason for the review was to update this treatment and to discuss the 2015 American Heart Association/American College of Cardiology/American Society of Hypertension 2015 guidelines of treatment of hypertension in patients with CAD.
Areas Covered:
Studies between 1968 and 2015 were reviewed on treatment of hypertension in patients with CAD using a Medline search, and studies between 1977 and 2015 were reported. Hypertension should be treated with beta blockers and ACE inhibitors or angiotensin receptor blockers (ARBs). Long-acting nitrates are effective antianginal and anti-ischemic drugs. Calcium-channel blockers (CCBs) may be added if angina persists despite beta blockers and long-acting nitrates. The 2015 guidelines recommend that the blood pressure should be < 140/90 mm Hg in patients aged ≤ 80 years and the systolic blood pressure < 150 mm Hg if they are ≥ 80 years.
Expert Opinion:
Hypertension in patients with CAD should be treated with beta blockers and ACE inhibitors or ARBs. Long-acting nitrates are effective antianginal and anti-ischemic drugs. CCBs may be added if angina persists despite beta blockers and long-acting nitrates. The blood pressure should be < 140/90 mm Hg in patients aged < 80 years and the systolic blood pressure < 150 mm Hg if they are ≥ 80 years.
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