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Complex Coronary Interventions with the Novel Mozec™ CTO Balloon: The MOZART Registry

Alessandro Lupi1, Andrea Rognoni1, Alon Schaffer2

  • 12nd Division of Cardiology, "Maggiore della Carità" Hospital, Novara, Italy.

Clinical Medicine Insights. Cardiology
|September 18, 2015
PubMed

Insights

The novel Mozec™ CTO balloon catheter effectively treats complex coronary lesions, including chronic total occlusions (CTOs), with high success rates. This device shows promise for complex lesion interventions in an all-comers population.

Area of Science:

  • Interventional Cardiology
  • Medical Device Technology
  • Vascular Surgery

Background:

  • The Mozec™ CTO is a new balloon catheter designed for complex coronary lesions like chronic total occlusions (CTOs).
  • Limited data exist on its performance in a diverse patient group with complex coronary artery disease.

Purpose of the Study:

  • To evaluate the safety and success rate of the Mozec™ CTO balloon catheter.
  • To assess its performance in an all-comers population with complex coronary lesions.

Main Methods:

  • The study included 41 consecutive patients with complex coronary lesions.
  • Lesion types comprised severe calcified stenoses, bifurcation lesions, and CTOs.
  • Safety was measured by balloon burst rate; success was defined as device advancement past the lesion.

Main Results:

  • High success rates were observed: 93.3% for calcified lesions, 93.3% for bifurcations, and 90.9% for CTOs.
  • Low balloon burst rates were reported across all lesion types.
  • The device successfully crossed challenging calcified and CTO lesions.

Conclusions:

  • The Mozec™ CTO balloon catheter demonstrates promising results for treating complex coronary lesions.
  • It may offer a cost-effective alternative to specialized devices like over-the-wire balloons and microcatheters.
Abstract

Keywords:
balloon catheterbifurcationcalcified coronary artery diseasechronic total occlusioncoronary angioplasty

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